Objective: To conduct a budget impact analysis on Sunitinib, provide references for its reimbursement policy on Urban Medical Insurance Plan. Methods: Budget impact analysis model was constructed to measure the expected changes in the expenditure of medical insurance system. Results: If Sunitinib could be reimbursed since 2015, the increase rate of medical insurance budget on mRR patient in 2015-2019 will be 18.5%, 23.1%, 27.8%, 32.4% and 37.0%. Conclusion: Reimbursement of Sunitinib will increase the total budget of medical insurance, and linear correlation was found between increase rate and variables.