Objective: To design the internal control process and link of the self service payment mode, to ensure the safety of hospital funds. Methods: Using internal discussion and reference to other units of the experience of the method, a comprehensive analysis of the key points of the self-service payment model, the process, the use of information means to carry out the whole process of design. Results: The key points and processes involved in the self-service payment model are controlled to ensure the safety of the funds. Conclusion: Internal control process should be designed to adapt to changes in the hospital payment model, and improve the internal control process to ensure the safety of hospital funds.