Objective: To analyze the factors influencing the price adjustment of medical services in Jiangsu Province，and to establish a model for measuring the total price adjustment of medical services in Jiangsu Province，so as to provide references for the establishment of a quantitative and sustainable mechanism for regulating the total price of medical services in China. Methods: On the basis of combing the experience and practice of total price adjustment measurement in other regions，the gross regional product growth rate，the increase of total medical insurance financing are selected as the main influencing factors to analyze the five-year data from 2016 to 2020. Results: The main factors affecting the growth of medical income of medical institutions include the growth of gross regional product，the urbanization rate of the population in the last year，and the growth of medical insurance financing. Conclusion: In practice，the factors that affect the calculation of the total price adjustment should be divided into non-negotiation factors and negotiation factors. The seabove three factors are regarded as non-negotiation factors，and the total price adjustment should be reasonably determined on the basis of comprehensive consideration of negotiation factors.