Under the social background of the increasing burden of chronic diseases, the importance of constructing a multi-level medical security system for chronic disease management has become increasingly prominent. In view of the diversified chronic disease management needs, Yuhuan People’s Hospital Health Community Group cooperates with government units, institutions of higher learn- ing, third-party institutions and other units to explore in the fields of payment of medical insurance funds according to curative effect, grass-roots financial compensation mechanism, commercial insurance, special needs services, and tries to build a multi-level medical security system for chronic disease management. It introduces the current medical insurance support policy of chronic disease manage- ment, the status quo of grass-roots operation problems and the innovative practice of Yuhuan, which provides the pilot experience for various localities in improving the support of the whole closed-loop management of chronic diseases.